John William Lowery (born July 31, 1971), best known by the stage name John 5, is an American guitarist. His stage name was bestowed on him in 1998 when he left David Lee Roth and joined the industrial metal group Marilyn Manson as their guitarist, taking over from Zim Zum. Still going by the name "John 5", Lowery has since become the guitarist for Rob Zombie.

He is also a solo artist having recorded seven guitar albums: Vertigo (2004), Songs for Sanity (2005), The Devil Knows My Name (2007), Requiem (2008), The Art of Malice (2010) and God Told Me To (2012), Careful with that Axe (2014), as well as a remix album, Remixploitation (2009). He also works as a staff writer for Chrysalis Records, working with artists such as Matt Ball, Avril Lavigne, Rob Halford, k.d. lang, Garbage, Meat Loaf, Scorpions, Ozzy Osbourne, Slash, FeFe Dobson and has written and recorded with southern rock band Lynyrd Skynyrd.